Top left: ALMA Band 3 continuum image from E. A. C. Mills et al. (2021), tracing a mix of free–free continuum emission from ionized gas, dust thermal emission from compact gas clouds, and synchrotron emission from supernova remnants. Top right: continuum-subtracted and integrated emission from the H5α line tracing ionized gas with units of 10⁶ MJy sr⁻¹ km s⁻¹. Bottom left: MIRI-MRS continuum image of the central starburst of NGC 253 at 4.9 μm, primarily showing stellar emission, with units in MJy sr⁻¹. Bottom right: continuum-subtracted and integrated emission from the H₂ S(5) line tracing warm molecular gas with units of 10⁶ MJy sr⁻¹ km s⁻¹. Cluster positions from E. A. C. Mills et al. (2021) for the 14 clusters identified from A. K. Leroy et al. (2018) are plotted as white x-shaped points and numbered in the top left panel. The position of SSC 6 is shown as an oversized cyan x. The circle indicates the region that is further extracted for analysis in this work.